John Nusstein Selected Research

Pharmaceutical Preparations

2/2019	Ibuprofen and Acetaminophen Versus Intranasal Ketorolac (Sprix) in an Untreated Endodontic Pain Model: A Randomized, Double-blind Investigation.
12/2016	Pain Reduction in Untreated Symptomatic Irreversible Pulpitis Using Liposomal Bupivacaine (Exparel): A Prospective, Randomized, Double-blind Trial.
9/2016	Does Liposomal Bupivacaine (Exparel) Significantly Reduce Postoperative Pain/Numbness in Symptomatic Teeth with a Diagnosis of Necrosis? A Prospective, Randomized, Double-blind Trial.

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John Nusstein Research Topics

Disease

36	Pain (Aches) 07/2022 - 01/2003
22	Pulpitis 12/2021 - 10/2003
11	Postoperative Pain 01/2019 - 01/2003
8	Hypesthesia (Numbness) 12/2016 - 10/2003
7	Necrosis 10/2018 - 12/2011
3	Periapical Periodontitis (Apical Periodontitis) 02/2019 - 10/2018
1	Acute Pain 02/2019
1	Abscess 04/2014
1	Cellulitis 04/2014
1	Paresthesia (Dysesthesia) 02/2004

Drug/Important Bio-Agent (IBA)

30	Anesthetics (Anesthetic Agents)IBA 12/2021 - 01/2003
22	SolutionsIBA 07/2022 - 01/2003
19	Lidocaine (Xylocaine)FDA LinkGeneric 04/2021 - 10/2003
17	Epinephrine (Adrenaline)FDA LinkGeneric 12/2021 - 10/2003
7	Carticaine (Articaine)IBA 12/2021 - 01/2004
6	Ibuprofen (Motrin)FDA LinkGeneric 02/2019 - 03/2010
6	Acetaminophen (Paracetamol)FDA LinkGeneric 02/2019 - 05/2011
5	Nitrous Oxide (Laughing Gas)IBA 12/2021 - 05/2012
5	Oxygen (Dioxygen)IBA 12/2021 - 05/2012
4	Local AnestheticsIBA 01/2018 - 01/2004
4	Mannitol (Osmitrol)FDA LinkGeneric 01/2014 - 01/2011
3	Pharmaceutical PreparationsIBA 02/2019 - 09/2016
3	Analgesics (Analgesic Drugs)IBA 10/2018 - 12/2011
3	Sodium Bicarbonate (Baking Soda)FDA LinkGeneric 06/2015 - 01/2010
2	KetorolacIBA 02/2019 - 01/2018
2	TabletsIBA 01/2019 - 10/2008
2	Opioid Analgesics (Opioids)IBA 02/2018 - 12/2016
2	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 12/2016 - 09/2016
2	Narcotics (Narcotic Analgesics)IBA 12/2016 - 09/2016
2	Mepivacaine (Carbocaine)FDA LinkGeneric 09/2014 - 02/2004
2	hydrocodone drug combination acetaminophen (Vicodin ES)FDA LinkGeneric 01/2014 - 12/2011
1	Clonidine (ST 155)FDA LinkGeneric 04/2021
1	Methylprednisolone FDA LinkGeneric 10/2018
1	Biomarkers (Surrogate Marker)IBA 05/2018
1	Prilocaine (Citanest)FDA LinkGeneric 05/2018
1	Hydrocodone (Dihydrocodeinone)FDA LinkGeneric 01/2014
1	BuffersIBA 11/2013
1	PlacebosIBA 10/2011
1	Phentolamine (Z-Max)FDA LinkGeneric 10/2011
1	Triazolam (Halcion)FDA LinkGeneric 10/2008
1	Meperidine (Pethidine)FDA LinkGeneric 01/2007
1	Amsacrine (AMSA)IBA 07/2004

Therapy/Procedure

18	Anesthesia 01/2022 - 01/2003
5	Injections 12/2021 - 02/2004
5	Debridement 01/2019 - 03/2016
2	Local Anesthesia 03/2009 - 10/2008
1	Premedication 01/2018
1	Therapeutics 01/2017
1	Endodontics 04/2014
1	Nerve Block (Nerve Blocks) 02/2010
1	Conscious Sedation 10/2008